Whole-Genome Alignment: Methods, Challenges, and Future Directions

Whole-genome alignment (WGA) is a critical process in comparative genomics, facilitating the detection of genetic variants and aiding our understanding of evolution.This paper offers a detailed overview and categorization of WGA techniques, encompassing suffix tree-based, hash-based, click here anchor-based, and graph-based methods.It elaborates on

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Malignant Trigeminal Nerve Sheath Tumor and Anaplastic Astrocytoma Collision Tumor with High Proliferative Activity and Tumor Suppressor P53 Expression

Background.The synchronous development of two primary brain tumors of distinct cell of origin in close proximity or in contact with each other is extremely rare.We present the first case of collision tumor with two histological distinct tumors.Case Presentation.A 54-year-old woman presented with progressive atypical left facial pain and numbness fo

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Accumulating exercise and postprandial lipaemia

Cardiovascular disease is a major cause of death in many developed countries.Impaired clearance apac1/60/1/cw of postprandial triacylglycerol has been associated with an increase in cardiovascular disease risk.Physical activity can reduce many cardiovascular disease risk factors including postprandial triacylglycerol concentrations.Public health gu

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Word sense disambiguation of acronyms in clinical narratives

Clinical narratives commonly use acronyms without explicitly defining their long forms.This makes it difficult to automatically interpret their sense as acronyms tend to be highly ambiguous.Supervised learning approaches to their disambiguation in the clinical domain are hindered by issues associated with patient privacy and manual annotation, whic

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